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Although marginally significant, the higher mean recombination found in B493 may help explain its larger observed total map length.
Although the higher mean recombination found in B493 may help explain its larger map length, other factors -e.g., related to the type of markers used- may also cause this effect.
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Nevertheless, we found that the mean recombination frequency was consistently decreased in all tissues examined (dentate gyrus, olfactory bulb, and DRG, data not shown).
However, when comparing mean recombination rates between polymorphic and nonpolymorphic TRs, the rates for the former were found to be significantly greater than the latter (P value for two-sample t test for means = 2.2E−16, 1.4E−07, 8.4E−09, and 2.1E−08 for mono-, di-, tri-, and tetranucleotide TRs, respectively; supplementary table S9, Supplementary Material online).
The mean recombination rate between the haplotype strands was set to 0.3, which is in line with the number of expected recombinations assuming one recombination per Morgan.
- recombination rate: The mean recombination rate along the genome in Homo sapiens is around 1.3 cM/Mb [ 11].
Mean recombination rate per bp in a 10 Mb telomeric region for all autosomes was compared to overall mean recombination rate per bp.
Chromosome mean recombination rate estimates (and confidence intervals) within scaffolds are reported in Table 1.
Table 2 shows the mean recombination rate across all SNPs for each group.
Mean recombination rates were plotted along the physical map of a chromosome.
Mean recombination rate varies sixfold between ontology-based gene classes [ 11].
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