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Mean ratios from the experimental dataset were also compared to the population of randomized values to determine whether the mean ratios obtained in the experimental dataset could have occurred by chance in the randomized datasets and significance levels (P-values) were assigned.
The results are presented as mean ratios from independent experiments for each cell line, compared to mean ratio obtained for the control sample (Table A4, Additional file 1).
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GMR: Geometric Mean Ratio from multivariate linear regression model.
Error bars represent the SD of the mean ratio from 100 cells.
Finally, the mean ratio from all tiling probes representing one barcode was determined.
Tumour DNA with a ratio outside the 95% confidence interval (CI) of the mean ratio from 30 normal controls was considered as positive for LOH in the p53 gene (representative results by DHPLC are shown in Figure 1).
A shift in distribution toward IgG2 was apparent in the PsA-TT group, as indicated by the decrease in IgG1 IgG2 mean ratio from week 4 to week 40 (P <.0001; Table 3).
Furthermore, empirical formulations for ice resistance on icebreaking vessels were combined with "max-to-mean ratios" from physical tank-model tests to estimate peak loads.
Two-tailed P values were derived to test whether the mean IgG1 IgG2 mean ratios differed from 1.0.
The p-values reflect significance of the differences between mean ratios obtained from the undiluted subpool-0 and the indicated dilution factors.
The mean ratio for all loci from all subjects is indicated by the black bar.
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