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A one-sample two sided t test with corresponding confidence interval will be used to determine whether the mean rate difference as calculated over all matched pairs is statistically different from zero.
dKa is the mean rate difference between the two lineages.
So the pattern of about half of the qualitative rate comparisons showing a faster substitution rate for annuals is consistent with random variation about a mean rate difference of zero.
Sample size estimates are based on the primary outcome of health status as measured by the CRQ [ 23], expressed as the mean rate difference between intervention and control groups.
To adjust the mean rate difference in PMR between groups for variables that show some residual imbalance after pair-matching, a multiple linear regression model will be used, with the rate difference between matched clinics as the dependent variable and variables with baseline differences between matched clinics as the independent variables.
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We then examined the correlations between the mean rate differences of domain pairs that are conjoined in multidomain proteins and the same domain pairs found in different proteins.
Conservatively, using the adjusted model for all-viruses mean concentration, all ages, the estimated mean incidence rate difference was 0.2 episodes/person-year. Dividing by the mean total AGI incidence from all transmission routes including tap water (mean IT) yields an attributable fraction of 11%.
Repeating the analysis using the unadjusted model for NoV-GI mean concentration, all ages,, the mean incidence rate difference is 0.45 episodes/person-year, which corresponds to an attributable fraction of 22%.
The main outcome measure was the mean growth rate difference in AAA diameter in mm/year between pharmacotherapy and control groups and expressed with standard deviations (SD) or related measures of dispersion.
We also computed the mean cesarean rate difference between multiple births before 34 weeks and after 36 weeks of gestation.
We calculated the mean cesarean rate difference between very preterm and term singleton births and between near term and term singleton births.
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