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I should have asked about these at every visit and once a year done a rectal exam to assess prostate size and look for cancer.
We report that the Bio 87.20 hamster strain (Bio Breeders, Watertown, Massachusetts) shows 5α-reductase-sensitive prostate enlargement and a decrease in circulating cholesterol reduces prostate size.
ADT is initially effective, reducing both prostate size and prostate-specific antigen (PSA) levels, but ultimately all patients become resistant to hormonal manipulation [4].
Prostate size was assessed using transrectal ultrasound.
The prostate size increases due to hyperproliferation of stromal and epithelial cells of the prostate gland.
In this model, prostate growth is restricted by the homeostatic prostate size.
A difference in mean prostate volume existed (P<0.001).
The mean prostate volume for PCa cases was 46.09 cm.
The rapid development of PIN and prostate cancer in conjunction with the large prostate size makes the SV-40 Tag rat a useful model for studying prostate cancer.
These figures disregard the - σP crowding term as this varies depending upon prostate size.
Another reason for their popularity is that their effects are independent of prostate size.
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