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Specifically, the mean probe space varied depending on the length of the tiled region.
For regions smaller than 100 kb (93% of the regions), the mean probe space was 50 bp; for regions between 100 and 300 kb (5%), probes were separated by 150 bp on average and finally, for regions longer than 300 kb (2%), mean probe spacing was 1 kb.
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The set array contains ~262,000 (Nsp I array) and ~238,000 (Sty I array) SNPs (mean probe spacing = 5.8Kb, mean heterozygosity = 27%%).
The Affymetrix GeneChip Human Mapping 500 K array set contains ~262,000 (Nsp I array) and ~238,000 (Sty I array) SNPs (mean probe spacing = 5.8 Kb, mean heterozygosity = 27%).
Finally, we used a very high-density array (mean probe spacing of 214 bp) to interrogate 241 deletion-CNV and 105 gain-CNV regions identified by the 2.1M array across the 7 test strains.
The mean probe spacing was 2557 bp and the median probe spacing was 2586 bp.
aCGH was carried out using the Agilent 244K chicken array with a mean probe spacing of 4000 bp.
The SNP genotyping resolution was 50.9 kb (mean probe spacing), whereas that of the aCGH platform was 6.3 kb.
The NimbleGen whole genome oligonucleotide microarray contains 386,165 isothermal probes (45 75-mer 45 75-merg the human genome at a mean probe spanningof 7 kb.
The chip contains 12 individual lanes, each spotted with 136,929 oligonucleotide probes with a mean probe spacing of approximately 560 bp.
We quantified copy number by hybridizing DNA to Nimblegen3x720K CGH array (http://www.nimblegen.com), which provided an evenly distributed coverage of ~720,000 oligonucleotide probes (mean probe spacing: 3,364 bp, array No. GPL17177).
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