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However, motifs that are exclusively part of abundantly expressed genes will also have high mean probe intensities and ranks.
Interestingly, shifts in mean probe intensities for data obtained from the same Operon V 3.0 probeset vary depending on the T7 primer used.
We ranked the mean probe intensities
Gender : for females and males separately, the mean probe intensities across SNPs on chromosome X.
Comprehensive RNA degradation plots of individual mean probe intensities indicated comparable transcript integrity across all samples and culture periods (Additional file 1a).
Note that under this construction, we achieve that b i = 0 is equivalent to no difference in mean probe intensities between Groups 1 and 2. We normalized data from each of the 100 simulations using SNM, QN and ISN. Figure 2 presents representative histograms of P-values of null probes after normalization using SNM (Fig. 2A), QN (Fig. 2C) and ISN (Fig. 2E).
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It is remarkable that the shift in mean probe intensity for the selected probes in fig 3 is so specific to the platform-primer combination studied.
This can for instance be seen in fig 3A where a much smaller shift in mean probe intensity is observed for those populations of probes that carry motifs from related, nearly identical T7 primers.
Mean probe intensity was determined for genes represented by more than one positive probe.
B) Melanoma samples were separated into DNMT1-low (<0.7 fold mean probe intensity level, n = 57) and DNMT1-high (>1,3 fold mean probe intensity level, n = 48), and a Kaplan-Meier plot was obtained for the two corresponding groups of patients.
Log-ratio thresholds for amplification and deletion were set at 1.5 standard deviations from the mean probe intensity.
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mean staining intensities
mean peptide intensities
mean probe recoveries
mean probe peaks
mean fold intensities
mean signal intensities
mean background intensities
mean foreground intensities
mean puncta intensities
mean rainfall intensities
mean infection intensities
mean pixel intensities
mean probe signals
mean spot intensities
mean dose intensities
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