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The mean predicted population density in 2015 was higher in the highly vulnerable conservation scenario (Table 1).
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To control for selection bias we calculated LS means, which are predicted population margins, estimating the marginal means over a balanced population.
Table 4 shows predicted population means (least square means) for each component of metabolic syndrome with adjustments for matching, lifestyle and dietary factors, other fatty acids, and BMI.
The predicted population mean of C-peptide AUC by treatment group over time was calculated to display the impact of treatment on delaying the decline of C-peptide (Fig. 2 B ). Considering the entire 3-year observation period, the estimated lag time in the means of the abatacept group to drop to the same level as the placebo group is 9.5 months (95% CI 3.44 15.7), P = 0.0011.
The effects of hormonal replacement therapy were reflected by the values of the predicted population margins or LS-means.
In the cross-validation, the observed versus predicted population variability around the population mean shows no obvious bias or skewness.
The dashed lines are the predicted population size.
Prediction errors were computed that provide a measure of bias and precision by assessing the differences between the measured and population mean predicted concentrations.
In our supporting online material (http://www.cs.rpi.edu/~drinep/POPRESAIMS, Text S1) we included plots for each of the eleven largest populations in our sample showing the mean and the standard deviation for each of the predicted populations.
The mean predicted risk of pneumonia in the Coventry population was 11%95%5% confidence interval 10%to13%3%) compared with an observed proportion of 12% (11% to 13%).
The overall mean score on the VAS of general health state was 77.1 (48 90), and the mean predicted for an age- and sex-matched UK population was 83.1 (70.7–83.1).
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