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In the present study, we found a mean percent decrease in the HAM-D of 54.3% ± 26.1 at 2-weeks post-treatment.
On treatment, mean percent decrease from baseline in SUVmax (DiSUV) was calculated for each patient and timepoint by averaging the percent decreases observed for all target tumors.
The primary endpoint was the proportion of patients in the R/R arm having a mean percent decrease from baseline in SUVmax (DiSUV) greater than 20% 12 14 days postdose in P2.
However, another smaller trial observed a mean percent decrease in SUVmax of target lesion(s) of only −11.1% (range 0 to −24.4) after 2 weeks of cetuximab given before radiation therapy and concurrent cetuximab [ 12].
For example in a previous study we reported [ 42], using transcranial magnetic stimulation, to treat 37 refractory depressed patients over two weeks, and used the same 21-item HAM-D as in the present study, and found at 2-weeks following the completion of the treatment a mean percent decrease in HAM-D of 29.4% ± 26.1.
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At Week 26, canagliflozin 100 and 300 mg were associated with mean percent decreases in eGFR relative to placebo in patients <65 years of age (-1.6%, -3.0%, and -0.6%, respectively) and those ≥65 years of age (-2.6%, -2.9%, and -0.4%, respectively).
The investigators found that the least squares mean percent atheroma volume decreased from baseline in patients treated with pioglitazone but increased in patients treated with glimepiride (−0.16 vs +0.73%, respectively, p = 0.002).
An increase in triglycerides (LS mean percent changes of 11.9, 6.2 and 7.9%, respectively) and a decrease in low-density lipoprotein cholesterol (LDL-C; LS mean percent changes of –1.0, 6.4 and 6.3%, respectively) were seen with canagliflozin 300 mg compared with canagliflozin 100 mg and placebo.
Among both cases and controls, the mean percent MD decreased with age, but in each age group the mean percent MD was higher among cases versus controls (Table 2).
Figure 2 shows mean A1C values and percent decrease throughout the study.
Values are listed as mean percent viability reduction.
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mean percent change
mean percent difference
mean percent mortality
mean percent improvement
mean percent error
mean percent blood
mean percent density
mean percent increase
mean percent dehydration
mean percent energy
mean percent recovery
mean percent signal
mean percent emphysema
mean velocity decrease
mean percent identity
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