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Their use of TZDs peaked on average to 0.117 (=11.7%) of all anti-diabetic drugs with mean peak time being 26 months.
Furthermore, this graph shows that the (mean) peak time for tissue TAC and trapped tracer TAC is 84 and 88 min, which could serve as landmarks to determine the optimal injection-acquisition time delay in clinical practice.
Indeed, all but two clusters enriched in these factors had a mean peak time of ≤22 hours.
The resulting vector angle indicated the mean peak time for each individual rhythm, and the magnitude of the vector (r) indicated the phase coherence.
After a meal, the postprandial glucose peak mostly occurs between 1 and 2 h with a mean peak time of 75 min (9).
The early gametocyte clusters detected in circulating parasites (clusters 13, 44, 81, 95 and 110) had a mean peak time of <20 hours post-invasion, suggesting similar gametocyte sequestration dynamics as those measured for asexual parasites.
Similar(53)
The two immature gametocyte clusters (clusters 95 and 125) with evidence for in vivo expression had among the earliest mean peak times within the set of immature gametocyte clusters (based on the NF54 gametocyte time course [ 30]).
We also identified four clusters (clusters 13, 20, 81 and 110) with mean peak times between 0 and 20 hours post-invasion, suggesting that these clusters are active in very young gametocytes.
Six of these clusters (clusters 224, 249, 255, 256, 266 and 272) had mean peak times between 41 and 51 hours post-invasion, suggesting that these are putative committed schizont clusters.
They contained a reduction in mean amplitudes of the scotopic a-wave (rod cone response), the scotopic oscillatory potentials (OPs)—OP2 and OP3, the photopic b-wave, and reduction in the overall index (OP1 + OP2 + OP3) and a prolongation of mean peak times of the scotopic OP1, OP2, OP3, and OP4 (p < 0.05).
They contained a reduction in mean amplitudes of the scotopic a-wave (rod cone response), the scotopic oscillatory potentials (OPs)—OP2 and OP3, the photopic b-wave, and a reduction in the overall index (OP1 + OP2 + OP3) and a prolongation of mean peak times of the scotopic OP1, OP2, OP3, OP4 (p < 0.05).
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