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The results of measurements of bone density (bone densitometry) are usually expressed in terms of the patient's bone density in relation to the mean peak bone density of people of the same sex and genetic background.
Osteopenia is defined as bone density that is more than one standard deviation below peak bone density (T score −1), and osteoporosis is defined as bone density that is two and a half or more standard deviations below the mean peak bone density (T score −2.5).
As previously pointed out, the World Health Organization has defined osteoporosis as a BMD of 2.5 standard deviations (SD) below the mean peak bone mass of young healthy adults (Table 1) (grade A recommendation).
Often, extent of bone loss experienced during this period results in osteoporosis (>2.5 SD below mean peak bone mass of average young adults) or osteopenia (1.0 2.5 SD below mean peak bone mass of average young adults).
The authors described OP as a bone mineral density (BMD) of 2.5 standard deviations below the mean peak bone mass as measured by dual-energy X-ray absorptiometry.
Osteoporosis is defined by the World Health Organization (WHO) as a BMD of 2.5 standard deviations or more below the mean peak bone mass (average of young, healthy adults) as measured by dual-energy X-ray absorptiometry.
Similar(52)
In animals operated on with implantation of netilmicin-loaded bone, mean peak concentrations were 4.2 [3.7 4.7] μg/mL 2-3 h postoperatively, whereas vancomycin could not be detected at all in serum.
The T score represents the number of standard deviation differences between an individual's bone mineral density versus that of the mean of the population at peak bone mass.
Building peak bone mass during childhood and adolescent can be the best means of preventing osteoporosis in older age.
Although no significant change in BMD T-score (based on peak bone mass) was seen, the Z-score (age-adjusted difference from the mean) did fall more rapidly than in control patients.
Data are presented as mean ± SD (25 percentile, median, 75 percentile) BMD, bone mineral density; BMAT, bone marrow adipose tissue; PBM, peak bone mass younger group; PoBL, potential bone loss older group.
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