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For simplicity, we choose the mean pairwise error penalty and, therefore, can set (alpha _i =frac{1}{i}).
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1 Present day Yakuts, Number of samples, Number of haplotypes, MPD: mean pairwise differences, Standard error.
h - haplotype diversity, π - nucleotide diversity (= mean pairwise distance, observed; standard errors based on bootstrapping), mean pairwise GTR distance.
Following [8], we use pairwise error probability (PEP) to bound average probability of error.
To test for selection Tajima's D was calculated as the difference between the mean pairwise nucleotide differences and the number of segregating sites (S) relative to their standard error using the software DnaSP v5.10.
The pairwise error probability is given as [30] (C.1).
Nearest neighbor pairwise error approximation can be used for efficient error rate evaluation.
Part B: Mean pairwise differences.
5 Mean pairwise differences per kb.
The mean pairwise difference in lengthening achieved was 10 (0–20) mm.
Unweighted mean pairwise distances were obtained from SplitsTree v4.
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