Non-uniform subcomponent sizes, imbalance between the contribution of various subcomponents of a problem, and the interaction between subcomponents by means of overlapping subcomponents are among these features.
The difficulty in designing conserved Pestivirus primers for the amplification of genomes from highly divergent isolates simply by means of overlapping segments is demonstrated using new bioinformatic tools.
The bones are fully ossified and the vertebrae interlock with each other by means of overlapping processes.
Indeed, disorder provides a solution to reduce both genome size and molecular crowding, where a single gene would (i) encode a single (regulatory) protein product that can establish multiple interactions via its disordered regions and hence exert multiple concomitant biological effects, and/or (ii) would encode more than one product by means of overlapping reading frames.
The desired mutations were introduced either by means of overlapping PCR (Additional file 1 Figure S1) or by site-directed mutagenesis.
This approach allowed us to test for shared neural substrates by means of overlapping activation for the two task components similar to previous studies (LaBar et al., 1999; Pollman & von Cramon, 2000: Corbetta et al., 2002; Lepsien et al., 2005; Ikkai & Curtis, 2011; Soto et al., 2008) and, in addition, by means of analysing interaction effects between the attention and WM manipulations.
The mean fraction of overlapping targets for genes identified as participating in cooperative binding was 10-fold greater (0.21) than the mean fraction of overlapping targets at genes that do not bind cooperatively (0.02) which is highly statistically significant (p < 2×10−16, Wilcoxon test).
Validation of the model indicated that the mean correlation of overlapping miRNA with their host genes is only marginally improved by performing scaling.
To solve the overlapped problem of MCI, the mean values of overlapped pixels are adopted for motion compensation.
The mean genomic distance of overlapping blood brain cis-eSNP from the probe TSS was 38.5 kb (not including proxy SNPs) – substantially less than the 121 kb average distance for brain eQTL reported by Gibbs et al. [ 7].
