The mean DASH score was 7 (0–26) for this subset of patients, compared to the mean normative DASH score for the uninjured population of 10.
Respondents from the UK had significantly greater mean normative misperception scores compared with those from Australia, Canada or the US.
Unlike HAD, ANI and MND are defined by performance at least 1 SD below the mean of normative scores in at least two cognitive areas; these criteria specify that at least five of the cognitive domains are examined or observed.
ANI is identified by performance on formal neuropsychological testing that is at least 1 SD below the mean of normative scores in at least two cognitive domains out of at least five examined in patients without associated symptoms or evident functional impairment in daily living.
Direct scores of Rey-copy test [ 75] were transformed in Z-scores corrected by age following Taylor scoring criteria [ 76]: (each subject score – mean normative data)/SD normative data.
In comparison to the social and emotional domains measured by the ITSEA in the normative population (mean normative T = 50), children in our sample generally had lower scores on assessments of externalizing behavior problems, internalizing behavior problems, and dysregulation (indicating fewer behavior problems; age- and sex-adjusted domain T-scores: 47.8, 45.1, and 43.0, respectively) (Table 1).
As the standard errors for the published norm scores were very small, the mean values of the normative scores were used to represent the 'real' values for the population of each age and sex group.
According to recently updated research definitions of HAND, Asymptomatic Neurocognitive Impairment (ANI) is defined by performance at least 1 SD below the mean of demographically adjusted normative scores in at least two cognitive areas, with at least 5 cognitive domains measured.
†SF-36 PCS (physical component) and SF-36 MCS (mental component) normative scores: mean 50 (SD 10).
At baseline, mean SF-36 MCS scores across treatment groups were 0.5 SDs lower than US normative scores of 50 (range: 45.7 47.0), whereas SF-36 PCS scores approximated 50 (range 48.6 49.3).
