Sentence examples for mean methylation of from inspiring English sources

Our results show that mean methylation of some of the differentially methylated sites in the VEGF, FLT-1 and KDR promoters were positively or negatively associated with their gene expression levels.

We observed that mean methylation of the VEGF promoter and some differentially methylated sites in the VEGF and FLT-1 promoters were associated with term and preterm gestations.

SI includes information on the quantitative levels of methylation at CpG sites 6367 and 6389 in the LI gene and on CpG sites 4238, 4247, 4259, 4268 and 4275 in the L2 gene and has the form S1 = 36L1 + 64L2, where L1 and L2 refer to the mean methylation of the two sites in L1 and the proportion methylated of the five sites in L2, respectively.

For analysis of age-associated DNA methylation changes we have calculated mean methylation of samples from young and elderly donors.

Supporting Information Fig 2 gives the mean methylation of the remaining investigated CGIs.

The mean IGF2 DMR methylation of Wharton jelly (P = 0.001) was statistically significantly higher than the mean methylation of MNC.

Non-neoplastic brain samples had mean average methylation of 3.2±2.89 s.d.

The mean methylation (number of methylated CpGs divided by the total number of CpGs in all analyzed alleles) was 94.6 ± 2.7% for GTL2, 1.5 ± 0.3% for PEG3, 92.3 ± 0.4% for OCT4, and 96.4 ± 0.2% for NANOG.

A regression analysis of the mean methylation levels of all samples, which diminishes the influence of outliers, results in an even better concordance (r2 = 0.957, slope: 0.9317, 95% confidence interval: 0.9078 to 0.9556, data not shown).

Affinity-based methods allow for rapid and specific assessment of the mean methylation levels of large DNA regions.

The LINE-1 pyrosequencing assay allowed the quantification of the mean methylation percentage of four consecutive CpG sites in the LINE-1 promoter region (GenBank accession number X58075), as previously reported [ 60].