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However, mean lung strain was ≥ 0.27 for each tidal volume.
The mean lung strain was < 0.27 with ventilation at tidal volumes of 6 and 8 ml/kg.PBW, whereas it was > 0.27 with volumes of 10 and 12 ml/kg.PBW.
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Introduction: Mechanical ventilation is associated with ventilation induced lung injuries (VILI) due to lung stress and lung strain.
As compared to supine, prone position increases resting lung volumes and decreases dynamic lung strain.
High values of dynamic lung strain (lung deformation caused by Vt) and static lung strain (lung deformation caused by PEEP) are associated with ventilator-induced lung injury [32, 37].
Greater lung strain and lung inhomogeneities increase the energy delivered to the respiratory system by the tidal volume.
For a given stress, lung strain may be completely different depending on the size of the lung.
We hypothesized that in ARDS patients, PP increases lung volumes (i.e., functional residual capacity and end-expiratory lung volume) and might decrease lung strain [16, 18].
These allowed to analyze the variation in lung volumes and to estimate lung volume recruitment and lung strain in both supine and prone positions in patients with ARDS.
Lung strain was calculated as the ratio between tidal volume and EELV.
Moreover, the change of position from supine to prone decreases dynamic lung strain.
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