The mean quality level achieved by the CMPD for the 10 Directory of Clinical Databases criteria was 3.4 (on a scale of 1 = worst to 4 = best).
The mean glucose level achieved during closed-loop control was 7.8 m M and was within the range associated with the lowest mortality in observational studies [ 5, 36].
Even in the controlled setting of statin trials, the mean LDL cholesterol level achieved in patients with diabetes is about 90 mg/dL (16).
Furthermore, whereas the mean LDL-C level achieved in the aggressive statin group was 2.95 mmol/l, current guidelines recommend that LDL-C reduction below 1.8 mmol/l is reasonable [ 28].
However, the mean TT levels achieved at months 3, 6, and 12 of TRT were not significantly different among the groups; thus, the quartiles differed in change in TT, but not in mean TT levels, during TRT.
Incremental areas under the curve for hormones were calculated by subtracting the mean hormone levels achieved during euglycemia (first 40 min of the clamp) from subsequent hormone levels during the rest of the clamp.
Level achieved: Pro Parent.
Insulin sensitivity was assessed as the mean glucose infusion rate over the last 40 min of the clamp, corrected for mean plasma insulin levels achieved during the same period (M/I, in micromoles per minute · per kilogram of free fat mass [FFM] per nanomoles per liter).
Insulin sensitivity was assessed as the mean glucose infusion rate over the last 40 min of the clamp, corrected for the mean plasma insulin levels achieved during the same period.
The mean plasma FFA levels achieved with lipid infusion correlated closely with all plasma endothelial activation markers: ICAM (r = 0.38, p = 0.03), VCAM-1 (r = 0.48, p < 0.01) and E-selectin (r = 0.48, p < 0.01).
