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Furthermore, mean intercept lengths and mean numbers of particles are measured and discussed.
Differing mean intercept lengths for different 3D angles indicate an anisotropic spatial organisation [ 55].
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Mean intercept length (MIL) method has been designed for the analysis of binary images.
In vivo cyclic loading significantly increased the bone volume fraction, direct trabecular thickness, mean intercept length, and mineral apposition rate in the loaded limbs compared with contralateral limbs.
A novel mathematical approach based on a Minkowski tensor analysis along with the mean intercept length technique were utilized to search for signatures of anisotropy across the foam sample and its evolution as a function of loading.
Current methods of extracting quantitative metrics from these types of images include localized vector analysis [21], Fourier transform [24], mean intercept length and line fraction deviation methods [23].
The degree of anisotropy (DA) was calculated as the maximum to minimum mean intercept length ratio.
Mean intercept length method was used to calculate trabecular bone volume, Tb.N and Tb.Sp. of the distal femoral epiphysis (covering secondary spongiosa and the secondary ossification center), proximal tibial and lumber 5 vertebrae.
It is calculated by performing a mean intercept length analysis, in which a grid of lines is basically sent through the binary void space over a large number of 3D angles.
Mean intercept length method was used to calculate trabecular bone volume, Tb.No and trabecular separation of the distal femoral epiphysis (covering secondary spongiosa and the secondary ossification center) and proximal tibialmetaphysis.
The degree of anisotropy, a measure of the degree of structural orientation of the trabecular network, can be calculated from the principal structural directions calculated by the mean intercept length techniques [ 63] and is highly related to the directional dependence of bone's biomechanical properties [ 115].
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