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The mean initial rSO2 value of the three patients with good neurological outcome was 44% (±26).
A tendency towards higher mean initial rSO2 in S compared with NS was observed together with a negative correlation between mean initial rSO2 and time between the EC and start of ALS.
We observed a negative correlation between mean initial rSO2 and time between EC and ALS (correlation coefficient -0.243; P = 0.041).
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The mean initial pp65 level was significantly higher in patients with concomitant CMV EOD versus those without concomitant CMV: 314 cells versus 13 cells, P<0.0001.
Mean initial 24-h dose was calculated by dividing the cumulated dose during the first 24 h by the cumulated duration of catecholamine administration during the first 24 h after ICU admission.
Excluding the remaining tissue category, the three source regions with the highest mean initial 18F activity uptake (defined as that at the initial imaging time point which was nominally 2 min p.i). were the liver at 18.3 ± 2.9% (range 15.6 23.8%), the lung at 5.1 ± 0.8% (range 3.9 5.9%) and the kidney at 4.5 ± 0.5% (range 3.8 5.1%).
Excluding the remaining tissue category, the three source regions with the highest mean initial 18F activity uptake were the liver (18.3%), lung (5.1%) and kidney (4.5%) and the highest mean normalised cumulated activities were the urinary bladder contents and voided urine (1.057 MBq h/MBq), liver (0.129 MBq h/MBq) and kidneys (0.065 MBq h/MBq).
On average, patients had 1 to 2 hyperglycemic periods during the study, with a mean initial A1C of 8.3%.
The mean initial ScvO2 value was 74.1 ± 11.0% and was not different between survivors and non survivors at day 28 (74.6 ± 10.0% versus 73.0 ± 12.9%, respectively; P = 0.21).
The mean initial CD4 was 320 cell/mm3, we observed 17 cases of maculopapular exanthema and 2 case of DRESS, the hepatic cytolysis retouved in 5 cases.
Their mean initial A1C, blood pressure, and LDL cholesterol at the beginning of the respective uncontrolled periods was 8.1%, 140/78 mmHg, and 126.8 mg/dL (Table 2).
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