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The mean dose was 0.7 µg/kg/h and the mean infusion time was 50 h.
Treatment was administered over a mean infusion time of 10 min (SD 6, range 3 to 30).
Focusing on the mean infusion time only, the difference in favor of nab-paclitaxel (27.50 ± 5.00 minutes versus 105.00 ± 70.36 minutes) is even more noteworthy.
The mean infusion time for Infusion 1 was 4.4 ± 0.3 hours, and approximately 12% (41/338) of patients receiving rituximab 1000 mg at Infusion 1 required more than 4.5 hours of infusion time.
Mean infusion time for hydration was 33.2 (SD 29.6) minutes for breast cancer, 36.6 (SD 26.4) minutes for prostate cancer, and 34.6 (SD 27.8) minutes for both cancers combined.
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Mean total infusion time was 218 ± 77.9 min (mean ± standard deviation, SD).
Mean ZA infusion time was 33.9 (SD 15.1) minutes for breast cancer, 29.4 (SD 12.1) minutes for prostate cancer, and 32.2 (SD 14) minutes for both cancers combined.
Results from this study confirmed that ZA infusion combined with ancillary tasks associated with IV infusions resulted in a total administration time that was much longer (mean 69.4 minutes; median 60 minutes) than the minimum infusion time stated in the Zometa label.
Overall, it was found that the mean time for ZA infusion, including hydration, was much higher than the minimum infusion time specified in the Zometa package insert.
The mean input time (MIT) was 66 min calculated from, where R0 and Tin denote the infusion rate and infusion time of the two consecutive cefadroxil infusions.
Respective mean infusion durations were 27.1, 35.4, 22.2, and 25.3 hours.
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