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This is reflective of the cohort study by Greenough et al. [24] and Shefali-Patel [22], which provided the mean incremental resource use for this period for infants with CLD and 33 35 wGA, respectively.
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These additional costs arise from a number of factors, including use of specific resources such as mechanical ventilation, which had a mean incremental cost in a US study of US$1,522 per day [ 12].
Incremental resource use for the mid preterms was extrapolated from Greenough et al. [24].
The mean incremental cost in FM patients exceeds those in the reference group by more than €5,000, of which only €600 was for the utilization of healthcare resources.
Mean incremental QALYs were subsequently derived.
The mean incremental costs were weighted against the mean incremental effect in terms of QALY.
The mean incremental costs were weighted against the mean incremental effects in terms of QALY.
Table 4 shows mean incremental QALYs and mean incremental costs compared with treatment as usual.
Finally, mean incremental costs, QALYs and the incremental cost-effectiveness ratio (ICER) were derived.
Mean incremental cost per patient and the incremental cost utility ratio (ICER) will be calculated.
For calculation of the ICER, mean incremental policy costs will be divided by the mean incremental QALYs.
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