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Moreover, carriers homozygous for Gc2 had significantly lower mean incremental glucose concentrations at 60 and 120 min 70.
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The low-GL test breakfast led to 43% and 27% lower mean post-prandial glucose and insulin responses, respectively; mean incremental areas under the curve for glucose and insulin, respectively, were 64.3±21.8 (mmol/L/240min) (p<0.01) and 2253±539 (μU/mlowermin) (p<0.01) lower following the low- compared to the high-GL test meal.
Acute insulin response to glucose (AIRg) is a parameter of early pancreatic response to glucose, calculated as the mean incremental plasma insulin concentration over baseline in the first 8 min of the FSIGT (14 ).
AIRg was calculated as the mean incremental insulin response above basal between 2 and 10 min after the intravenous glucose bolus was started.
cThe incremental glucose value at 3 min after glucose injection.
Mean incremental QALYs were subsequently derived.
The mean incremental costs were weighted against the mean incremental effect in terms of QALY.
The mean incremental costs were weighted against the mean incremental effects in terms of QALY.
Table 4 shows mean incremental QALYs and mean incremental costs compared with treatment as usual.
Finally, mean incremental costs, QALYs and the incremental cost-effectiveness ratio (ICER) were derived.
Mean incremental cost per patient and the incremental cost utility ratio (ICER) will be calculated.
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