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The mean incremental charge was $8,202 (range: -57,384 to 226,864) in the 423 patients who continued treatment for between 25 and 47 weeks and $6,249 (range: -207,548 to 130,297) in the 372 patients who completed 48 weeks of PEG-IFN-alfa/ribavirin treatment.> -wrap-foot> hepatitistitis C virus; PEG-IFN-alfa, pegylated interferon alpha.
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The mean incremental TEC charge for this group was $7,509 (range: -29,273 to 292,904).
In the analyses from both perspectives the mean incremental health care costs were weighted against the mean incremental effect in terms of quality adjusted life years (QALY).
Mean incremental QALYs were subsequently derived.
The mean incremental costs were weighted against the mean incremental effect in terms of QALY.
The mean incremental costs were weighted against the mean incremental effects in terms of QALY.
Table 4 shows mean incremental QALYs and mean incremental costs compared with treatment as usual.
Finally, mean incremental costs, QALYs and the incremental cost-effectiveness ratio (ICER) were derived.
Mean incremental cost per patient and the incremental cost utility ratio (ICER) will be calculated.
For calculation of the ICER, mean incremental policy costs will be divided by the mean incremental QALYs.
Although neither the mean incremental cost nor the mean incremental QALYs reach an arbitrary 5% significance level, the probability of an intervention being cost effective is determined from a joint assessment of incremental costs and incremental QALYs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com