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Mean increases from baseline to day 2 were 22.93 msec and 14.65 msec, respectively.
Patients experienced normal growth as assessed by mean increases from baseline in height and body weight.
Tofacitinib treatment in pooled Phase 3 studies over 12 months resulted in mean increases from baseline in SCr levels.
Tofacitinib treatment in pooled RA phase-3 studies over 12 months resulted in mean increases from baseline in serum creatinine (SCr) levels [ 7].
Mean increases from baseline in plasma total zeaxanthin and all- E-zeaxanthin Cmax were significantly higher (p < 0.01) in response to SMB as compared to AMB (Table 2).
The maximum mean increases from the preantiemetic baseline for QTcF and heart rate were 10.1 msec (upper 90% CI, 14.5 msec) and 18.2 beats per minute, respectively.
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The mean increased from 22.10 to 48.62 mg/g with an increase in dye concentration.
Among those who had at least 1 publication, the mean increased from 1.3 to 2.2 (range 1 15).
This finding was confirmed by intracellular cytokine staining of primed CD4+ T cells (Figure 5B), as there was a significant increase in IL-17+/IFN-γ− single positive CD4+ T cells (mean increase from 4.6% to 9,7%, n = 5 experiments; P = 0.004) and IL-17+/IFN-γ+ double positive CD4+ T cells (mean increase from 1,1% to 9,7%; n = 5 experiments; P = 0.002), (Figure S4).
On day 7, the mean increase from day 0 for DHA/PQP had fallen to 10.47 msec with the value for AS+MQ being 13.39 msec; this difference was not statistically significant (p = 0.075).
At 85 minutes post-patch removal, the mean increase from pretreatment was 5.2 mm Hg.
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