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On day 7, the mean increase from day 0 for DHA/PQP had fallen to 10.47 msec with the value for AS+MQ being 13.39 msec; this difference was not statistically significant (p = 0.075).
This finding was confirmed by intracellular cytokine staining of primed CD4+ T cells (Figure 5B), as there was a significant increase in IL-17+/IFN-γ− single positive CD4+ T cells (mean increase from 4.6% to 9,7%, n = 5 experiments; P = 0.004) and IL-17+/IFN-γ+ double positive CD4+ T cells (mean increase from 1,1% to 9,7%; n = 5 experiments; P = 0.002), (Figure S4).
At 85 minutes post-patch removal, the mean increase from pretreatment was 5.2 mm Hg.
Quantitation of apoptosis by AnnexinV/Hoechst staining demonstrated that, following treatment with 1 μ PBOX-15 for 24 h, apoptosis was induced in all samples with a mean increase from background levels of 12±2.9% (range 5 22.4%).
The mean increase from baseline to 3 years was 6.2 times (p < 0.001) (95% CI = 3.3 11.6), consistent with waning of responses between one and three years by a factor of 0.6 (p = 0.10).
Because of a within-session learning effect, the MCA exposure resulted in a mean increase from baseline (baseline mean = 32.72; SD = 9.1) of 2.10 points on the neurobehavioral task.
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The mean increased from 22.10 to 48.62 mg/g with an increase in dye concentration.
Among those who had at least 1 publication, the mean increased from 1.3 to 2.2 (range 1 15).
Mean increases from baseline to day 2 were 22.93 msec and 14.65 msec, respectively.
Patients experienced normal growth as assessed by mean increases from baseline in height and body weight.
Tofacitinib treatment in pooled Phase 3 studies over 12 months resulted in mean increases from baseline in SCr levels.
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