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Mean headache attack incidence per month was higher in females (2.9 ± 4.3) than in males (1.6 ± 3.0; P <0.0005 [Student's t-test]).
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The mean duration of the headache attack decreased in 2 of the 5 patients.
Figure 1 Mean headache intensity 1 during attack treatment for all four different triptans.
Fig. 3 Significant reduction in a mean headache severity during migraine attacks (p = 0.002); b HIT-6 questionnaire rating (p < 0.001) and c monthly intake of total rescue medication intake (p < 0.001), NSAID (including acetaminophen) (p = 0.02), and triptans intake (p = 0.04).
Mean age was similar between the two groups (about 44 years) and mean frequency of headache attacks in CH patients was about 2 attacks/day.
The mean frequency of headache attacks per month before pregnancy was 3.5, and in the first, second, and third trimesters of gestation, the mean frequencies were 2.3, 1.2, and 1.4, respectively.
The mean frequency of headache attacks, which was 6.3/month before treatment, fell to 1.7/month after treatment (P < 0.0001).
In a study of the prevalence and indirect costs of headache in a Brazilian company, the mean frequency of headache was 4.3 ± 7.0 attacks per month, and the mean headache duration was 12.2 ± 21.4 h [30].
Primary end-point of the study was the reduction of mean attack frequency; secondary end-points were the reduction of mean headache intensity and the increase of symptomatic therapy responsiveness.
The short duration of attacks and the low recurrence rate result in a significantly lower mean headache intensity in this study after 24 hours and 48 hours.
Mean headache frequency was 3.8 ± 6.2 days/month, mean headache intensity 2.1 ± 0.7 on a 0 3 scale, and mean attack duration 41.9 ± 108.5 h.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com