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Among the 12 sequenced GAS genomes, on average coding sequence constitutes 86.4% of each genome, with a mean gene size of 870 nt.
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This 266 Kb fragment of translocation includes 107 genes from Pc22g24360 to Pc22g25450 and their mean genes size is 1,638 bp.
In Figure 1(c), we can see this measure has the identical mean over the gene size.
The rate of Y Y gene conversion has been estimated to be 2 × 10−4 conversions per duplicated nucleotide per generation for multigene families lying within palindromes (Rozen et al. 2003), and we multiplied this number by the mean human Y gene size (∼2,000 bp, ENSEMBL GRcH37 for human data) to get a rate of gene conversion per gene (rGC) of 0.4.
We compared three kinds of gene-level measures,,, and In Figure 1, each plot shows the mean of gene-level measures over the gene size.
* Expected value calculated as (Mean gene length × Number of genes)/ sequenced genome size.
Mean gene variance, for instance, would be decreased if bicluster size is increased or the overlap decreases.
Genetic variation, characterized by AFLPs, was low (mean gene diversity, He: 0.126) and generally increased with increasing population size.
* Expected value calculated as (Mean gene length × Number of candidate genes)/ sequenced genome size.
In general, the four strains show small variations in their numbers of CDSs, mean gene lengths, and gene densities, which arise from differences in their genome sizes.
The relative uniformity of mean gene expression, from tissue to tissue, and their low variance indicates that the data are not limited by relatively small sample size.
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