Sentence examples for mean functional conservation from inspiring English sources

However, the sequence conservation does not necessarily mean functional conservation, so major candidate genes from different pathways have to be functionally characterized in order to prove the presence of these pathways in strawberry.

To examine the possibility of co-regulation acting as a selective force to maintain the RD gene cluster, the expression of the four RD genes was examined in D. melanogaster (which houses a semi-dispersed RD cluster) and in A. mellifera (which houses an intact 'ancestral' RD cluster) as a means of investigating functional conservation of RD gene orthologues between these species.

However, this lack of sequence similarity did not result in a lack of conservation by position, which could indicate a conservation of function as it has been shown earlier that positional conservation also accounts for functional conservation [ 15, 30].

Both HIF binding sites displayed high conservation across other vertebrate genomes, suggesting functional conservation (Supplementary figure S1).

In the following section, we therefore tested whether this conservation of sequence underlies functional conservation of these putative enhancers.

The functional conservation is consistent with the sequence homology and hinted at a structural conservation between both homologs.

This signifies a degree of functional conservation of mammalian and Drosophila Syx5.

Previous studies confirmed the functional conservation of syndecan in Drosophila [19].

We used a maize diversity panel to test the CCM functional conservation.

Here, we analyzed the functional conservation of the translocon β subunit and its TMD.

Functional conservation acts as a strong restraint limiting sequence and, even more, structural divergence [57].