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All patients were cognitively impaired: mean full scale IQ = 42.2, SD = 3.2 (range 40 58).
All individuals with autism were cognitively impaired (mean full scale IQ ± SD: 42.2±3.2, with range of 40-58; mean verbal IQ ± SD: 45.5±2.2; with a range of 45-57; mean performance IQ ± SD: 45.6±4.1, with a range of 45-57).
The mean full scale IQ prior to anti-TNF therapy was 103.8 (SD 10.6), which compares to an age- and sex-adjusted population mean score of 100 (SD 15).
At the last testing mean full scale intelligence quotient (FSIQ), verbal IQ (VIQ) and performance IQ (PIQ) were 89.1 (standard deviation SD 14.6), 94.0 (SD 12.4), and 86.2 (SD 16.1).
They did not differ significantly from the males with autism in age (mean years: ASD = 31 ± 13; controls = 31 ± 11; t-test P = 0.9) or overall intelligence as measured by the Wechsler Adult Intelligence Scale (Wechsler, 1981) (mean full scale: ASD = 115 ± 13; controls = 123 ± 20; t-test P = 0.2) (Table 1).
Boys obtained a higher mean full scale IQ than girls of 3.75 IQ points, a higher performance IQ of 4.20 IQ points, and a higher verbal IQ of 2.40 IQ points.
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In the present study, both tasks were presented to 24 participants who attended day services for people with learning disabilities (mean Full-Scale IQ = 59.8), half of whom were trained to use a visual aid to support decision-making.
Patients assessed with the SIPS were significantly older compared with patients who were not assessed with the SIPS (t = −3.423, p = 0.001), but did not differ regarding gender distribution (χ = 0.070, df = 1, p = 0.792), mean full-scale IQ (t = −0.515, p = 0.608) and mean BPRS positive symptom score (t = −1.460, p = 0.147).
Results: The mean full-scale IQ was 105.9 ± 14 for ICSI and 107.2 ± 12.9 for NB children which showed no significant difference.
The mean full-scale WASI scores, years of education, and ages for the groups appear in Table 6.
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