Sentence examples for mean fold rises from inspiring English sources

To assess vaccine versus placebo geometric mean fold rises in serum antibody titers, after controlling for potentially confounding variables, multiple linear regression models were fitted.

For the overall population, opsonophagocytic activity (OPA) assay titer geometric mean fold rises (GMFRs) ranged from 11.5 (serotype 3) to 137.2 (serotype 7F).

The primary objective was to evaluate immune responses to the PCV13 serotypes 1 month after dose 3 of PCV13, as measured by geometric mean fold rises (GMFRs) of the IgG geometric mean concentrations (GMCs) (GMFR postdose 3/baseline).

Although the vaccine vs. placebo differences in the geometric mean fold rise were statistically significant in both adults and children, the rise in antibodies was substantially less compared to V. cholerae O1 Inaba antibody titers.

BOLD : values of SPR and Geometric mean fold rise that did not meet the pre-specified criteria.

The seroprotection rate (SPR) was 95%, seroconversion rate (SCR) was 93%, with a corresponding geometric mean titer (GMT) of 175.1 and geometric mean fold rise (GMFR) of 20.

European Medicines Agency Committee for Medicinal Products for Human Use CHMPP) criteria for haemagglutination-inhibition antibody response in 18 60 year olds are: seroprotection rate >70%, seroconversion rate >40%, and geometric mean fold rise >2·5 and in adults >60 years are seroprotection rate >60%, seroconversion rate >30%, and geometric mean fold rise >2·0.

Table 3 illustrates baseline geometric mean titers (GMT), geometric mean fold rise (GMFr), and seroconversion rates as defined by a ≥ 4-fold rise in titers from baseline GMT to 14 days following the first and second doses.

Geometric mean titers were calculated, with any test-negative sample assigned to value of 5. Geometric mean fold rise was calculated as the within-subjects ratios of the post-vaccination HAI titer to the baseline HAI titer.

**Geometric mean fold rise is defined as geometric mean of the within-subject ratios of the post-vaccination reciprocal haemagglutination-inhibition titre to the Day 0 reciprocal agglutination-inhibition titre.

Results : At Day 21, the HI immune response met all three European guidance criteria [seroconversion rate (SCR): 60.0%; seroprotection rate (SPR): 64.0%; geometric mean fold rise (GMFR): 10.2] and the US guidance criterion for SCR.