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Maximum mean fold changes were 5 for PB blasts, >22 for CD34+ cells, and >38 for CXCR4+ cells by day −3 compared to baseline.
Figure 1a illustrates mean fold changes (in Log2) for transcripts included in each of the seven clusters and provides a general picture of how these differed between origins.
The graphs shown in Figs. 4, 5 and 6, which represent the mean fold changes, show the changing mRNA profiles for each breed over the entire time course.
Bar plots represent the mean fold changes and error bars the standard deviations.
The mean fold changes of the genes in the scaffolds including the h locus candidate region were visualised with IGV88,89 software (ver. 2.3.88).
Mean fold changes in mRNA levels were calculated relative to D30 PGC-like cells.
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Geometric mean fold-changes in gene expression for the BTB group were calculated by dividing the geometric mean CNRQ value for the M. bovis-infected group by the geometric mean CNRQ value for the control group.
Geometric mean fold-changes of gene expression (M. bovis-infected samples relative to control samples) are given for the RNA-seq sense strand, microarray and real time qRT-PCR data.
The heights of the red columns represent the logarithmically transformed mean fold-changes between the resistant and parental cells detected by QPCR.
Differences in mRNA levels are listed as mean fold-changes ± standard error.
This roughly gives respective values of 0.0 and 1.0 for the minimum and mean fold-changes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com