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Total EEG activity was assessed using the global mean field power (GMFP) [12], [42].
A comparison of the TMS-evoked response before and after rTMS conditioning revealed a significant increase in the amplitude of components comprised between 10 and 130 ms (Figure 1, gray area, p<0.05, paired t-test, average global mean field power (GMFP) between 10 and 130 ms).
To determine the best predictor of the local increase in SWA after 5-Hz rTMS conditioning, we calculated correlation coefficients for the components of the global mean field power of the TMS-evoked response in relation to the local increase of SWA.
In order to obtain the overall amount of electrical activity induced by TMS, we calculated the global mean field power (GMFP) (Lehmann and Skrandies, 1980) from the multichannel average signals as follows: where k is the number of channels, V i is the voltage measured with channel i, and V mean is the mean of the measured voltages across channels (average reference).
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They assessed total EEG activity using the global mean-field power (GMFP) and demonstrated that EEG responses to single TMS pulses delivered to motor cortex are increased in amplitude following the rTMS, most profoundly at latencies of 15 50 ms.
To quantify the data we first calculated the grand mean time courses of two global measures of the magnetic response across subjects: the mean global field power (MGFP) for the magnetometers and gradiometers and the mean global dipole strength over the cortex (Figure 3).
Then, VEP data were recalculated off-line against the average reference, and normalized to their mean global field power (i.e., GFP [44], [45]).
VEP data were then baseline corrected, and band-pass filtered between 1 and 30 Hz. VEP data were then recalculated off-line against the average reference, and normalized to their mean global field power (i.e., GFP) before group averaging.
Table 1 shows the baseline and task-related root mean global field power changes, converted to SNR values, for both tasks, averaged across subjects.
The mean global field power (MGFP) was calculated separately for the magnetometers and the gradiometers by squaring the signal values and averaging them across sensors.
In this paper, the intraclass correlation coefficient (ICC) between mean global field powers (MGFPs) of each hemisphere is proposed to quantify long latency auditory evoked potential (LLAEP) interhemispheric symmetries as a measure of auditory cortex reorganization in CI recipients.
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