The faster evolving member of the pair was likely to show lower mean expression and higher coefficient of variance of expression across tissues, making it "less household" than the slower evolving copy.
ER, approximate mean expression ratio, NC, mean normed coefficients.
The table shows the number of genes in each TFBS class, approximate mean expression ratios (ER), mean normed coefficients (NC), and p-values from t-tests.
The table shows the number of genes in each class of motif, approximate mean expression ratios (ER), mean normed coefficients (NC), and p-values from t-tests.
Again, given that variance of the consecutive samples is enhanced by spread of the mean expression values, we expected smaller coefficients of the standard deviation function in combined comparison, which has higher density of the mean expression values.
Some expression patterns were quite similar; hence we calculated the correlation coefficient of the mean expression pattern between any two of the 12 clusters.
For each tissue, the genes were ranked according to their mean expression level, and the Pearson correlation coefficient of the expression ranks across all 13 tissues for any two genes was obtained.
Each patient's tumour sample was classified using a correlation coefficient based on the mean expression value of each selected gene for the pCR and non-pCR subsets.
Finally, a correlation coefficient was computed between the mean expression level of genes in each category and the number of coverage cutoffs or k-mer sizes per category.
As in previous studies, when we averaged gene expression levels across the single cells profiled in each condition, we observed that the mean expression levels recapitulated the bulk gene expression levels with a Spearman rank correlation coefficient of around 0.9.
