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The mean encapsulation efficiency (EE) of 82.47% was close to the predicted value of 89.69%.
The mean encapsulation efficiency of the drug in the prepared conventional liposomes, ethosomes, and transfersomes were 42.61 ± 3.62%, 51.72 ± 4.36%, and 46.73 ± 5.21%, respectively.
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The nanoliposomes were characterized by means of encapsulation efficiency and particle size.
Twelve operating factors were retained, and the particle properties considered were the mean size, the encapsulation efficiency, and the surface state.
The characteristics of optimized DMFL on encapsulation efficiency, mean diameter and pH value were 85.47 ± 0.83, 160.4 ± 0.55 nm and 6.58 ± 0.05, respectively.
Table 2 shows the experimental results concerning the two tested variables on mean particle size and encapsulation efficiency.
The prepared tLPTS/HATS NPs had about 110 nm in mean diameter, high drug encapsulation efficiency (93%), and sustained drug release behavior.
Two different means of enhancing the encapsulation efficiency and stability of AA were demonstrated: a pore blocking method and a micromolecule-chelating agent within the core.
The dependent variables were the mean particle size and the encapsulation efficiency.
The formulations were characterized in terms of morphology, mean diameter and siRNAs distribution, encapsulation efficiency, and in vitro release kinetics.
The nanoparticles properties considered were encapsulation efficiency (Y1), mean particle size (Y2), zeta potential (Y3), burst effect (Y4) and dissolution efficiency (Y5).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com