Sentence examples for mean dissociation constant from inspiring English sources

The affinity of 13 kBT corresponds to a mean dissociation constant larger than 1 µM, which is a very weak affinity between proteins and DNA.

Available experimental data indicated that the polymerase domain binds dsDNA (corresponding to our case as schematically shown in Figure 4B) with a mean dissociation constant of about 100 nM [40], which is equivalent to a binding affinity of about 16 kBT that is larger than 13 kBT.

The sera raised against 1xVSO1-100xELP bind to 100xELP with a > 15-fold higher mean dissociation constant.

Scatchard analysis of the binding data revealed a linear plot consistent with a single class of binding sites with a mean dissociation constant (Kd) +/- s.d.

Therefore, the complexity is also limited and calculation of a mean dissociation constant K d is a useful tool to characterize the immune response against ELP-based epitopes.

The calculated mean dissociation constant K d for the complex 1xVSO1-100xELP-anti 1xVSO1-100xELP from animal 1 and the competitor 100xELP was 25 nM and the mean K d for 4xVSO1-100xELP-anti 4xVSO1-100xELP from animal 5 and 100xELP was 374 nM.

Likewise, the mean dissociation constants (K D ) to FcRn, which regulates IgG catabolism, were determined by BLI as 2.58 E−07 M ± 1.02 E−07 M (CI 95%) for Trastuzumab-Probiomed with a relative binding affinity of 114.3% (n = 3) with respect to the reference product.

Values for the mean equilibrium dissociation constant (KD = koff/kon) were low and similar for DEPN-8 (104 nM) and DPPC (89 nM), showing that both lipids had substantial molecular affinity for the chip-linked Mini-B monolayer (Table 2).

Saturation analysis shows a single class of high-affinity binding sites that had a mean equilibrium dissociation constant (KD) of 15 nM for the SKOV-3 cell line.

Here, the mean dissociation rate is constant and therefore does not affect the profile of Jd, the drop of which is solely the result of the loss of free minus-ends towards the back (Figure S2B).

Levels of binding in individual tumours varied from 0.8 to 15 pmol mg-1 cytosol protein (mean value 5 pmol mg-1 cytosol protein) and the dissociation constant ranged from 0.5 to 5.2 X 10 -8)M (mean 1.73 X 10 -8 M).