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This calculation gives a mean coverage factor of 47 69.
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The mean coverage for the leptin gene was ~ 80× [26].
The results show that the fault coverage factor should be ≥0.8 and Mean Time To Repair (MTTR) should be ≤100 h in order to satisfy the requirement that the availability of the safety grade PLC should be ≥0.995.
Different factors of library complexity including total number of reads, number of viral reads, coverage and mean coverage depth across the genome (percentage consensus depth indicates areas in which depth is over 22).
Mean coverage of the targeted exons was 697X.
Coverage factor (its value lies between 0 and 1).
Mean coverage probabilities in per cent.
Black lines: mean coverage at common peaks.
Mean coverage: the mean number of reads per base.
Normalized coverage-distribution plots were calculated as follows: The mean coverage per exon was divided by the overall mean coverage of all exons as normalized coverage (x-axis).
To better distinguish CNVs from repetitive regions, we only allowed regions with one strain having a mean coverage around the mean genome coverage (±0.5* mean coverage).
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