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Exact(5)
The items showed appropriate characteristics (mean item-total-correlation: 0.46 ± 0.12; mean correlation with HbA1c: -0.23 ± 0.09).
let-7i, which was reported to be down-regulated and showed strong positive mean correlation with its targets, also had a low RR value (0.767).
miR-125b, which was reported to be down-regulated and showed strong negative mean correlation with its targets, had a relatively high RR value (0.958).
For example, miR-29a, which was reported to be up-regulated in prostate tumour and showed strong negative mean correlation with its targets, had a very low RR value (0.435).
Taking the mean correlation with human plague (D) per incremental increase in GCV underlines this, showing a very high correlation between GCV and mean D (ρ = -0.99, n = 27, P < 0.001).
Similar(55)
Tolerance estimates based on the used/available pressure gradient and the average general pressure value had the highest mean correlations with the expert judgment classification (mean r = 0.4) and with the other approaches (mean r of 0.48 and 0.46, respectively).
The second step was testing whether the UPDRS groups of items, as described above, had equal mean correlations with the VMC variables.
Items that showed the highest overall mean correlations with their corresponding criteria were chosen to be included in the scale.
We chose convergent validity as the main criterion so that final items (not only total scores, which are typically used in the validation of similar scales) were those that showed the highest mean correlations with their respective validation measures across countries.
Note that the correlations corresponding to the most significant entries in the mean correlation matrix (with absolute values greater than 0.5) are statistically present in all individual correlation matrices because corresponding standard deviations are relatively small (less than 0.2).
The Table 12 shows that the subset of markers extracted from group 8 showed higher mean correlation 0.84 with a standard deviation slightly lower 0.07 for the PUK kernel.
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