Sentence examples for mean conversion tract from inspiring English sources

We show that modeling overlapping gene conversions is crucial for improving the joint estimation of the gene conversion rate and the mean conversion tract length.

We believe that this aspect of our model is crucial in making the joint estimation of the gene conversion rate and the mean conversion tract length feasible.

We can see that estimates of γ can be substantial although the true value is 0. When the mean conversion tract length becomes longer (e.g., 2000 bp, 8000 bp), we observe multiple peaks in the joint posterior distribution.

We show that this simplification frequently leads to gross errors in the estimation of the gene conversion rate and the mean conversion tract length, when all three parameters are being estimated.

In all simulations, we used θ = 1.0/kb for mutation rate and λ=0.5 kb for the mean conversion tract length, both of which being relevant to humans [see Ptak et al. (2004) and Frisse et al. (2001), respectively].

In their article, Gay et al. did not try to estimate the mean conversion tract length, but always fixed it to some reasonable value (actually, the true value in the case of simulation study).

Mean gene conversion tract lengths were estimated to be 476 base pairs, yielding a per nucleotide conversion rate of 0.86 × 10−5 per meiosis.

Of 41 HR repair events analyzed, the average gene conversion tract was 471.4 bp (±73.8).

Thus they should mention that their data gives a range of 100-1000bp buthesese values provide no indication on the mean value of gene conversion tract length.

In these cases, analysis of GC variation could provide some information on the parameters of meiotic recombination, like the mean length of conversion tracts, and capture some characteristics of the history of meiotic recombination (hence sexuality) of a given lineage.

The conversion tract length is assumed to follow a geometric distribution, and λ denotes the mean of that distribution.