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The mean concentrations with the acceptable ranges of 2 SRM levels were 65.4 (66.5 ± 1.9) and 343.9 346.22 ± 7.3) μmol/L, respectively.
Analysis of Variance (ANOVA) on the logarithms of the geometric mean concentrations (with 0.1 added to every value to avoid attempting to take logs of zero) was undertaken using the statistical package GenStat [ 7], examining the contributions of plant, 14 broad job groups and calendar year.
The total estimated intake based on mean concentrations (with values < LOD imputed as one-half LOD), was highest for DEHP (0.673 μg/kg/day) followed by DBP (0.184 μg/kg/day), whereas estimated total mean intakes of all other phthalates were ≤ 0.1 μg/kg/day.
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The detected mean concentration with standard deviation (mean ± SD) of diazinon was 16.58 ± 49.13 μg/l (Table 2).
IgG concentrations (µg/mL) against the individual serotypes were calculated from the mean fluorescence intensity by interpolation of the plot from the reference serum, 89-SF, and expressed per group as geometric mean concentration with 95% confidence intervals.
For instance, in each run of simulation the concentration of CC can be assumed to be a random number generated based on a log-normal distribution around its mean concentration with a CV of 0.25.
For each study participant's home address the back extrapolated concentration was obtained by multiplying the modelled ESCAPE annual mean concentration with the ratio between average annual concentrations as derived from the routine monitoring site(s) for the period in the past and for the ESCAPE measurement period time (details can be found in www.escapeproject.eu/manuals/) [ 12].
In females, total testosterone (available at baseline and week 8) increased in a dose-dependent manner with mean concentrations within the laboratory reference range.
Carriers of the rs3918342 T allele (both C/T and T/T) had 50 nmol/l lower HVA mean concentrations compared with C homozygotes; no difference in HVA mean concentrations was found between C/T and T/T (Fig. 2).
Although mean serum trough concentrations were higher with each dose, the increase in mean concentrations is smaller with each successive dose as steady-state is reached.
To facilitate comparisons with previous literature, ion concentrations are presented as mean concentrations in μg/L with 95% confidence intervals (CIs).
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