Sentence examples for mean combination index from inspiring English sources

Sequential treatment of tumor cell lines resulted in synergistic antiproliferative activity in 77.78% of the combinations tested, with a mean combination index of 0.44 (95% CI = 0.39 to 0.50).

The mean combination index for the combination of α-TEA + DOXO was 0.41 ± 0.07 and 0.53 ± 0.05 for MDA-MB-231 and BT-20 cells, respectively (Table 3).

The mean combination index for the combination of α-TEA + CDDP was 0.45 ± 0.10 and 0.75 ± 0.08 in MDA-MB-231 and BT-20 cells, respectively (Table 3).

A mean combination index of 0.8 was found in our experiment confirming the existence of slight synergistic (supra-additive) cytotoxic activity (Fischel et al, 1998).

Figure 1 shows the dose response curves for SHSY5Y cells in each of seven schedules and Figure 2 shows the mean combination index (CI) values plotted against fraction of cells affected.

A mean combination index (according to Chou and Talalay, 1984) of 0.4 was found, which confirmed the existence of the previously reported synergistic cytotoxic activity (Magné et al, 2002a).

By means of their combination index values obtained via checkerboard microplate method, a formulation showed superior activity to that of compound 3 alone.

GF: Griseofulvin; IC50: half-maximal proliferation inhibitory concentration; MAPs: microtubule associated proteins; FITC: fluorescein isothiocyanate; EGFP: enhanced green fluorescent protein; RMSD: root mean square deviation; CI: combination index; TNP-GTP: 2',3'-O- 2,4,6-trinitrocyclohexadienylidene) guanosine 5'-triphosphate The authors declare that they have no competing interests.

A combination index at 1.00 means simple additivity, below 1 means synergy and higher than 1 means antagonism.

Interaction between the double combinations was assessed by means of an automatically computed combination index (CI).

Interaction between the double combinations (ZD1839 plus either cisplatin or 5-FU), or the triple combinations (ZD1839 plus cisplatin and 5-FU) was assessed by means of an automatically computed combination index (CI).