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Bladder SMC had mean cell capacitance of 51.5 ± 1.5pF, n = 82.
The mean cell capacitance from the larger animals (body mass, 805 ± 34.2 g; heart mass, 1.01 ± 0.20 g) was 41.2 ± 2.3 pF (n = 55 cells).
The mean cell capacitance from the smaller animals (body mass, 67 ± 3.3 g; heart mass, 0.29 ± 0.02 g) was 42.2 ± 6.2 pF (n = 16 cells).
Considering a mean cell capacitance of 240 pF, a typical maximum current density of 5 to 10 pA/pF (see Fig. 3B), and Rs (effective)<2 MΩ, the voltage error was <2.4 to <4.8 mV.
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Furthermore, the FO-fed rabbits did not show any signs of myocardial hypertrophy: mean values of cell capacitance were160±15 and 159±6 pF for control and FO myocytes (n = 20 and 33, p>0.05).
The mean value of cell capacitance was 19 pF±5 (total number of experiments n=20).
Fig. 6C and D shows the mean effect of MCD on cell capacitance and outward current, respectively.
where Cm = 10 pF is the cell capacitance.
The capacitance arises from the cell capacitance, the double-layer capacitance and the capacitance of the poly-l-lysine-coated surface, and the changes in capacitance were probably due to cell proliferation and the resulting changes in cell metabolites.
Access resistance and cell capacitance were measured using on-line exponential fits to a capacitance transient (Membrane Test, Clampex).
Cell capacitance was measured for each cell, and access resistance compensated to ∼80%.
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