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We showed that increasing ambient temperatures from 20°C to 30°C would result in a more than tenfold increase in the mean burden of infection.
For every experiment liver-parasite burden was normalized to the mean burden of controls infected in the same experiment.
These results suggest that CRC patients carry a mean burden of ~300 cell equivalents of cancer-derived DNA/mL plasma (Table S1).
28 The sample size estimation was based on unpublished data on 23 extremely preterm infants with a mean burden of 76.0 (SD 83.2) %hours.
A mathematical model has recently been developed; for cattle carrying a mean burden of 20 30 tabanids per head, the model indicated that the probability of transmission becomes significant when parasitaemia is above 10 trypanosomes/mL [ 4].
If residential mobility was taken into account, the mean burden of illness estimates would not be impacted, but the results of the analysis would have less variability, with fewer estimates at the high and low ends of risk [ 9, 10].
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The patients took a mean of 3.9 psychotropic medications, with a mean pill burden of 7.2 for these drugs.
The 144 patients took a mean of 4.4 ± 2.1 psychotropic medications daily with a mean pill burden of 7.6 ± 5.3.
The patients in this study took polypharmacy with a mean of 3.9 psychotropic medications for bipolar disorder, and a mean pill burden of 7.2.
A study of 128 patients in the US [ 27] found they were taking a mean of 4.1 medications to control diabetes and an overall mean pill burden of 5.8 different medications.
For 29 of 31 assessed symptoms, patients who reported the respective symptom had a mean score of ≥ 2.0, and seven symptoms were reported to have a mean symptom burden of more than 2.6 (Table 3).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com