The local bone mineral density and the trabecular microstructural parameters, including the mean bone volume to total volume (BV/TV), trabecular thickness, trabecular separation, and structure model index (SMI), were measured using bone analysis software.
For trabecular bone, trabecular bone volume (Tb.BV), trabecular bone volume fraction (BV/TV), trabecular connectedness (Conn.D), trabecular thickness (Tb.Th), and trabecular number (Tb.N) were quantified via previously established algorithms [34].
Bone trabecular appeared discontinuous and lessen.
Trabecular bone volume, trabecular thickness and trabecular number of lumbar vertebral bodies were decreased after OVX.
If it is true that the presence or absence of trabecular bone mass reduction has an influence on the likelihood of response to treatment, it does not mean that trabecular bone loss is required for a hip fracture to occur, it simply increases the risk and may influence the type of fracture that occurs.
This would also mean that trabecular bone adaptation could be modeled as a system responding to an input signal at the onset of the process in a predefined manner, without feedback from the outputs.
The mean fractional trabecular bone volume of the ON group was 0.45 (± 0.07) (n = 8) whereas it was 0.51 (± 0.03) in the AMG treatment group (n = 8).
The mean trabecular bone volume constituted 28,4 ± 3,82% with a mean trabecular width of 225,12 ± 16,30 μm.
Mean trabecular area, mean trabecular perimeter and mean skeleton length were calculated by total trabecular area, perimeter and skeleton length in ROI relative to trabecular number, respectively.
Although the mean trabecular bone area in OA is higher than in OP, there was no statistical significance between them.
