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Threshold and response latency data were expressed as a percentage of the mean baseline values assessed during 5 days before each PCP/vehicle injection or prior to the implantation of the minipumps.
Mean baseline values for all demographic and dependent variables for the 2 treatment conditions were compared by t-tests.
Table 1 reports the mean baseline values for all enrolled patients, collectively and by group assignment, along with current age and age at onset of headache.
The mean baseline values of LV volumes, LV ejection fraction, heart rate, blood pressure and body weight were also similar between the three groups (Tables 1 and 2). Figure 1 Examples of FDG-PET images at 48 h, 1 month and 2 months in representative cases.
Values for each parameter over 10 minutes were summarized by the assessment of mean baseline values.
Analysis of variance with the Bonferroni correction was used to compare mean baseline values among the four groups.
Similar(23)
The mean baseline value of NO release was 63.3 ± 6.9 pmol/ml (mean ± SE).
The mean baseline value of VO2 significantly increased with volume expansion only in patients with ScvO2 > 70%% (Additional file 3: Table S2).
The detection threshold was set above the mean baseline value for the first 6-15 cycles.
Action potential threshold was defined as the point at which the derivative of the membrane potential dV/dt deviated from the mean baseline value by >2 standard deviations [46], and was calculated using routines developed in our laboratory (Figure S2).
The means were adjusted for dialysis unit location and the relevant mean baseline value.
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