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The mean apparent coefficient of diffusion (ADC) and grey matter volumes were measured in the whole brain.
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Viswanathan et al. [22] have used an integrated multi-modal model to determine the impact of WMHs, lacunar lesions, microhemorrages, mean apparent diffusion coefficient (ADC) and brain parenchymal fraction (BPF) on cognition and disability.
Mean apparent diffusion coefficient (ADCmean) of tumor was evaluated as the MRI parameter on the ADC map.
According to Gumustas et al. [8], the mean apparent diffusion coefficient for the malignant mediastinal entities could be significantly lower than that for the benign diseases.
Moreover, quantification of diffusion effects of the tumour using mean apparent diffusion coefficient (ADC) values also helps in characterization of these lesions.
Open image in new window Fig. 4 Bland-Altman plot from 10 pairs of baseline measurements of mean apparent diffusion coefficient (ADC) in ROIs copied from those later drawn in heated regions identified on PRFS after sonications.
Quantitative analysis with DWI may be of help as the mean apparent diffusion coefficient (ADC) of benign tumours (1.72 × 10−3 mm2/s is often higher than that of malignant tumours (1.05 × 10−3 mm2/s (P < 0.001) [26], with the exception of Whartin tumours, which typically show very low ADC values.
Mean apparent diffusion coefficient (ADC) was measured for each node.
In the 239 histologically proven metastatic lymphadenopathies, the mean apparent diffusion coefficient (ADC) value was 0.903 × 10−3 mm/sec.
Moreover, in a study by Sundgren, the mean apparent diffusion coefficient values were found to be significantly higher in the recurrence group.
The mean apparent diffusion coefficient of water within the tumour did not change, indicating that there was no expansion of necrotic regions during the 3 h after drug treatment.
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