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Prognostic variables associated with progression to death/lung transplantation were identified by using a Cox proportional hazards model.RESULTS: Mean annual decline of FEV1 was 89 ± 53mL/year and remained remarkably constant regardless of baseline lung function.
Mean annual decline in FEV1 % predicted, assessed over five years, was calculated as a linear regression slope, adjusting for potential covariates and stratified by smoking status.
Mean annual decline in post-bronchodilator FEV1 % predicted (%predFEV1)(11) was calculated as a linear regression slope using all available time points.
Mean annual decline of renal function will be calculated by regressing GFR or creatinine clearance against time.
Table 2 shows the mean annual decline for the different lung function parameters according to average BMI category.
MDT care has been associated with a lower mean annual decline in eGFR compared with usual nephrology care in CKD stage 3 [ 17].
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81 Although treatment with nintedanib and pirfenidone reduced the rate of decline in FVC, the mean annual declines in FVC in the pirfenidone and placebo groups were −235 mL and −428 mL, respectively, in the ASCEND trial, while the mean annual declines in FVC in the nintedanib and placebo groups in the INPULSIS trials were −95 mL and −205 mL, respectively.
One previous study in Taiwan reported that the mean ratios of HBeAg/HBsAg declined steadily from 1993 to 2000, with the mean average annual declines in HBeAg rate being 1.2%, 0.6%, 0.4% and 0.1% in those <26 years, 26 30 years, 31 35 years and >35 years, respectively [ 20].
This represents an average annual decline of 3.1% [ 1].
Finally, the association between mean annual percentage decline in mortality rates and area-level deprivation for local authorities was assessed.
The results showed that the mean annual temperature declined from 21.4 °C during the Gada period of Boru Guyo (1984 1992) to 20 °C during the Gada period of Boru Madha (1992 2000).
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