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Nonetheless, the mean alpha risk was <5% for both the tests and all genetic correlation values.
The mean alpha risk for the CI test was <5% for the 800 K assay.
In the present study, the multiplicative coefficient was fixed to 1, thus providing a mean alpha risk <5%.
The mean alpha risk of the CLIP test was equal to 3% or 4% depending on the setup.
The mean alpha risk of the CI test was equal to 6% for the 60 K assay and 2% for the 800 K assay.
Similar(55)
Mean alpha risks and powers for the CLIP and CI tests, which depend on the experimental design (that is, density of the SNP assay, number of individuals genotyped), are presented in Table 2.
Sequence in frame means Alpha-amylase_C domain.
The calculation of the sample size is carried out to compare means, with an alpha risk of 0.05 (95% confidence level) and a beta risk of 0.20 (80% power).
In order to achieve a 2.7% reduction between the estimated mean and the sampling mean with a statistical power equal to 90% and an alpha risk of 0.05, one hundred and fifty-three participants were necessary, being the rest of the variables correctly described and included for this sampling size.
Accepting an alpha risk of 0.05 and a beta risk of 0.1 in a bilateral contrast, and assuming a mean score of 16.07 and an SD of 4.19 [ 33] on the RBMT-3 in the Spanish population aged between 70 and 75 years, 75 individuals in each group will be needed.
For each test, the alpha risk was set at 0.05.
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