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Quantitative analysis of resting EEG recordings displayed an increased delta and/or theta activity, a decreased main frequency, a low mean alpha frequency ("hypofrontality") and an increased beta activity in schizophrenia patients [ 15, 26].
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For alpha ERP-analyses, frequency bands were adjusted to mean IAF individual alpha frequency.
We also like that it means alpha-bet (Alpha is investment return above benchmark), which we strive for!
Sequence in frame means Alpha-amylase_C domain.
The mean change in peak alpha frequency (PAF) will be the primary outcome measure to assess the effects of CV4 technique on nonspecific chronic low back pain.
The investigators hypothesize that CV4 technique can modulate brain cortex electrical activity measured by EEG mean change in the peak alpha frequency.
The aim of the study is to assess the CV4 technique effects on nonspecific chronic low back pain measured by the mean change in the peak alpha frequency (PAF).
In order to evaluate tACS-induced cortical modulation, the mean spectral amplitude within the frequency range of the individual alpha frequency (IAF) ±2 Hz was calculated (alpha band) and entered into a repeated-measures analysis of variance (ANOVA) with the between subject factor Group (tACS-group/Sham-group) and the within subject factor Measurement (Pre/Post).
Thus, alpha frequency stimulation should be largest in visual cortex areas, the generators for visual cortical alpha.
In conclusion, tACS at individual alpha frequency entrains brain activity in visual cortices.
We stimulate subjects at their individual alpha frequency (IAF, ~10 Hz).
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