For the groups combined, the mean age at peak height velocity was 16.1 y, and the SITAR tempo fixed effect showed this age to be significantly earlier in the calcium group by 0.62 ± 0.24 y (P = 0.01) or 7.4 mo (Table 3, Figure 3B).
The mean age of peak height velocity was 16.4 y for boys and 13.1 y for girls, which contrasts with estimates, for example, in the United States (boys/girls: 13.6/11.5 y) (28), Canada (boys/girls: 13.4/11.8 y) (29), and Switzerland (boys/girls: 14.5/12.5 y) (30).
Estimates of mean age at peak velocity were obtained by differentiating the mean growth curve and identifying the age when this velocity curve peaked; its SEM was assumed to be the same as that of the mean tempo random effect.
In the girls, the mean ages at peak height velocity were 13.3 and 13.2 y for the calcium and placebo groups, respectively.
The mean ages at peak height velocity for the 2 groups were 15.7 and 16.4 y, respectively, in the calcium group 0.7 y (8 mo) earlier.
The SITAR height distance and velocity curves for boys and girls are depicted in Figure 3, and the group differences in the estimated mean SITAR parameters for height, weight, and BMI are shown in Table 3 ; the mean ages at peak velocity are given in Table 4.
The mean age at infancy BMI peak was 7.2 months for boys and 7.4 months for girls; the mean BMI at infancy peak was 17.8 kg/m2 for boys and 17.3 kg/m2 for girls.
Methods: We studied by echocardiography Doppler 22 patients (mean age 12.4 ± 5.6 years) with peak and mean transvalvular gradient of 63 ± 6 and 32 ± 4 mm Hg, respectively.
The mean age and the age range of peak incidence are consistent with the current literature.
Mean age was 38 years with two peaks of incidence, women aged 18 to 29 years and 42 to 53 years accounting for 32%and38%8% respectively of the cohort.
