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Transplant to muscle ratios were calculated as the mean activity within these ROIs divided by the mean activity within ROIs drawn in muscle tissue.
After 60 min of recording following α,β-meATP injection, the mean activity within 10 min (new baseline) ranged from 20 to 1357 (mean 425, SEM ± 129) spikes/min.
However, in some cases, it might come in defect: for example, when overshoots of activity appear in the reconstructed images as a side effect of resolution modelling during reconstruction, or when images are extremely noisy, the max-count polar maps would assign to the PM values that are an overestimation of the actual mean activity within the LV.
To determine the relationship between subjects' numerical score improvements and mean activity within an ROI we computed their Pearson correlation.
If mean activity within the window lay outside a specified multiple of SDs from the baseline mean, this was considered significant EMG activity.
The group average F-values (represented by the color bars in the figures below) from the time course of the mean activity within each ROI were entered into a repeated-measures analysis of variance (ANOVA) with language (Spanish vs. English) and repetition (new vs. old) as within-subject factors.
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By this process, deviation from the biopsy mean activity concentration, within the sectioned sub-sample, had no influence over the final simulated sphere concentration.
The rationale was to study the frequency of microsphere clusters and the distribution of microsphere cluster sizes in relation to the mean activity concentrations within individual biopsies.
The mean activity concentration within the ROI was determined and expressed as the SUV, where SUV is the ratio of the activity in the tissue to the decay-corrected activity injected into the patient.
SUVmax and SUVmean were calculated using the maximum and mean activity values within each ROI on the transaxial slices with the highest radioactivity concentration, normalized to the injected dose and patient's body weight.
The predicted 90Sr and 137Cs mean activity concentrations were within an order of magnitude of the observed data means.
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