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35 A correlation between increase in mean absolute lymphocyte count while on therapy and greater clinical benefit has been reported.
The 2.5- and 5-mg doses of saxagliptin had no discernible effect on mean absolute lymphocyte count.
The mean absolute lymphocyte count was significantly higher in patients with Candidemia versus control patients, i.e., 1.13 × 10 cells/mm versus 0.61 × 10 cells/mm, respectively, (p = 0.02).
There was a small numerical decrease from baseline in mean absolute lymphocyte count in the 10 mg saxagliptin group (−0.14 × 10 cells/μl) without evidence of clinical sequelae.
They found that the mean absolute lymphocyte count in the patients with SAP was significantly lower than those with mild AP and concluded that the absolute lymphocyte count had an accurate predictive power for AP severity.
A Phase III study 26 observed a small and transient decrease in mean absolute lymphocyte count, which was not found to be associated with any increase in incidence of infections.
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The mean absolute total lymphocytes, CD3, CD4, and CD8 T lymphocytes, B lymphocytes and NK cells has increased from 1349 to 1870 cells/mm3, 1130 to 1268 cells/mm3, 511 to 591 cells/mm3, 440 to 547 cells/mm3, 120 to 152 cells/mm3, and 103 to 254 cells/mm3, respectively.
Furthermore, with the exception for B lymphocytes, the mean absolute numbers for total lymphocytes, CD3, CD4, CD8 T lymphocytes, and NK cells at 24 months after the onset of symptom remained statistically different from that in normal healthy age-matched controls.
In our study we found that females have significantly higher counts of absolute CD4 T cells and absolute CD8 T cells than males, and also higher mean absolute leukocyte and lymphocyte counts.
Compared with data from placebo recipients, the mean decrease in the absolute lymphocyte count was 100 cells/μL among recipients of 5 mg saxagliptin daily.
The results for the immunohaematological values are given in table 1 and 2 Reference value are reported in percentile Reference value are reported in percentile Reference values are reported in percentiles in these tables Females had higher mean absolute leukocyte counts and lymphocyte counts than males (table 2).
More suggestions(15)
mean absolute value
mean absolute percent
mean absolute power
mean absolute difference
mean micronucleated lymphocyte
mean absolute identity
mean absolute accuracy
mean absolute time
mean absolute Error
mean absolute percentage
mean absolute fitness
mean absolute calculation
mean absolute standard
mean absolute rotation
mean absolute deviation
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